Dialysate sodium and sodium gradient in maintenance hemodialysis: a neglected sodium restriction approach?

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Dialysate sodium and sodium gradient in maintenance hemodialysis: a neglected sodium restriction approach?

BACKGROUND A higher sodium gradient (dialysate sodium minus pre-dialysis plasma sodium) during hemodialysis (HD) has been associated with sodium loading; however, its role is not well studied. We hypothesized that a sodium dialysate prescription resulting in a higher sodium gradient is associated with increases in interdialytic weight gain (IDWG), blood pressure (BP) and thirst. METHODS We co...

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Dialysate sodium, serum sodium and mortality in maintenance hemodialysis.

BACKGROUND Individuals with end-stage kidney disease appear to have stable pre-dialysis serum sodium concentrations over time, with lower values associating with increased mortality. Dialysate sodium concentrations have increased over many years in response to shorter treatments, but the relationship between serum sodium, dialysate sodium and outcomes in chronic hemodialysis patients has not ye...

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Effect of dialysate sodium concentration and sodium gradient on patients with maintenance hemodialysis

Backgrounds: Patients with maintenance hemodialysis (MHD) have a high risk of cardiovascular disease, which is the leading cause of morbidity and mortality. The aim of the present study was to explore the relationship between the sodium gradient and the water load of MHD patients. Methods: Eighty one MHD patients were selected in the study. The serum sodium concentration, sodium gradient, inter...

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Sodium Gradient: A Tool to Individualize Dialysate Sodium Prescription in Chronic Hemodialysis Patients?

Low dialysate sodium concentrations have been associated with intradialytic symptoms such as muscle cramps and hypotensive episodes. High dialysate sodium concentrations lead to sodium loading, thirst and subsequent increase in interdialytic weight gain and hypertension. The optimal dialysate sodium concentration for an individual depends on the serum sodium concentration. The difference betwee...

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Sodium Gradient: A Tool to Individualize Dialysate Sodium Prescription in Chronic Hemodialysis Patients?

Low dialysate sodium concentrations have been associated with intradialytic symptoms such as muscle cramps and hypotensive episodes. High dialysate sodium concentrations lead to sodium loading, thirst and subsequent increase in interdialytic weight gain and hypertension. The optimal dialysate sodium concentration for an individual depends on the serum sodium concentration. The difference betwee...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2011

ISSN: 0931-0509,1460-2385

DOI: 10.1093/ndt/gfq807